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Imagine a cell that refuses to die. It sits in your tissues, metabolically active but permanently stalled in the cell cycle, spewing a cocktail of inflammatory signals that damage neighboring cells, disrupt tissue architecture, and accelerate the very aging process it was meant to protect against. These are senescent cells—often called "zombie cells"—and they represent one of the most promising ta
Evidence Assessment
Evidence Strength
Strong
Study Type
Systematic Review
Confidence
High
Key Findings
- The science of cellular senescence, the senescence-associated secretory phenotype (SASP), natural senolytic compounds (fisetin, quercetin), pharmaceutical senolytics, and current human clinical trial results
Practical Takeaways
- Review the evidence on senescence with your healthcare provider
- Evidence-based protocols are detailed in the full article
Limitations & Caveats
- Individual results vary
- Consult a healthcare provider before major interventions